pisco_log
banner

Measuring Mechanical Properties of Medicated Chewing Gum and Evaluating Chewing Efficiency for Different Shape Teeth

Zelin Li

Abstract


Medicinal chewing gum (MCG) is a relatively new drug delivery platform that offers significant advantages over traditional tablets.
However, the lack of suitable testing methods has slowed its adoption by the pharmaceutical industry. The official pharmacopoeia does not
recommend a formal test method to determine the mechanical properties of MCGs. This project uses a two-bite test method to assess the mechanical and textural properties of MCG to investigate the effect of experimental parameters on the results.

Keywords


Medicated chewing gum (MCG); Two-bite test; Texture profile analysis; Teeth shape

Full Text:

PDF

Included Database


References


[1] Al Hagbani, T., Nazzal, S. Medicated Chewing Gums (MCGs): Composition, Production, and Mechanical Testing. AAPS PharmSciTech

19, 29082920 (2018). https://doi.org/10.1208/s12249-018-1123-z.

[2] Rahman, M.S., Al-Attabi, Z.H., Al-Habsi, N., Al-Khusaibi, M. (2021). Measurement of Instrumental Texture Profile Analysis (TPA)

of Foods. In: Khan, M.S., Shafiur Rahman, M. (eds) Techniques to Measure Food Safety and Quality. Springer, Cham. https://doi.

org/10.1007/978-3-030-68636-9_17

[3] S. P. Ungar, Mammalian dental function and wear: A review, Biosurf. Biotribol., vol. 1, pp. 2541, 2015.

[4] P. W. Lucas, Dental Functional Morphology. How Teeth Work. Cambridge, U.K.: Cambridge Univ. Press. 2004. 355 2004, [Online].

Available: https://doi.org/10.1017/CBO9780511735011

[5] J. W. Osborn, Relationship between the mandibular condyle and the occlusal plane during hominid evolution: Some of its effects on

jaw mechanics, Amer. J. Phy. Anthropol., vol. 73, pp. 193207, 1987.

[6] J. W. Osborn, Orientation of the masseter muscle and the curve of Spee in relation to crushing forces on the molar teeth of primates,

Amer. J. Phys. Anthropol., vol. 92, pp. 99106, 1993.

[7] H. Fukoe et al., Three-dimensional analyses of the mandible and the occlusal architecture of mandibular dentition, J. Stomat. Occ.

Med., vol. 5, pp. 119129, 2012.




DOI: http://dx.doi.org/10.18686/frim.v2i3.4250

Refbacks

  • There are currently no refbacks.