pisco_log
banner

Construction of Responsive Nanocarriers and Their Key Role in the Development of Novel Sustained-Release Drugs

Haonan Dong

Abstract


Responsive nanocarriers enable controlled drug release by reacting to pH, temperature, enzymes, or light, improving efficacy and reducing side effects. Various carrier types achieve site-specific release, increasing drug accumulation at target sites. They show strong potential
in cancer, chronic disease, gene therapy, inflammation, and vaccine delivery. Studies confirm their advantages in targeting, release efficiency, and
biocompatibility. Despite challenges in degradation, stability, and scalability, they offer promising solutions for precise and personalized therapy.

Keywords


Responsive nanocarriers; Sustained-release drugs; Precision drug delivery; Targeted therapy; Biocompatibility

Full Text:

PDF

Included Database


References


[1] Xiong C Y, Lei Z X, Sun T L. Research progress on ROS-responsive nanocarriers for bacterial infection therapy[J]. Drug Evaluation

Research, 2024, 43(11): 1804-1812.

[2] Lu G L, Jin Y T, Liu X R, et al. Platinum drug delivery system based on stimulus-responsive polymer nanocarriers[J]. Polymer Bulletin,

2024, 37(10): 1317-1336.

[3] Han K S, Wang X L, Ren T, et al. Construction and evaluation of multifunctional nanocarriers loaded with nitrosoureas[J]. Chemical

Reagents, 2023, 45(09): 19-28.

[4] Li H, Zhang J B, Li J X, et al. Research progress on intelligent responsive nanocarriers for nucleic acid drug delivery[J]. China Pharmacy, 2022, 33(09): 1147-1152.

[5] Zhang Y L, Li G, Zhang X G, et al. Construction and performance of bacteria-responsive nanocarriers[J]. Ion Exchange and Adsorption,

2022, 38(02): 97-105.

[6] Zhang Y X, Wang J W. Research progress on responsive polymer nanomaterials as drug carriers[J]. Polymer Bulletin, 2021, (04): 1-6.

[7] Su Y H, Zhang W L, Shen Y, et al. Research progress on red blood cell-based nanocarrier drug delivery systems[J]. Pharmaceutical Research, 2024, 43(03): 255-260+281.

[8] Zhou W, Yang K G, Zhao B F, et al. ROS-responsive nanocarriers[J]. Chromatography, 2021, 39(02): 118-124.




DOI: http://dx.doi.org/10.70711/frim.v3i8.6956

Refbacks

  • There are currently no refbacks.