A study on Accuracy of a Reusable Probe and Regional Oximeter Based on Near-Infrared Spectroscopy During Controlled Hypoxia in Healthy Participants
Abstract
oximeter developed by Shenzhen Mindray Bio-Medical Electronics Co., Ltd.
　　Approach: The regional oximeter was connected and the supporting reusable near-infrared spectroscopy sensor was placed on 26 healthy
volunteers' forehead for rSO2 measurement. The participant's inspired oxygen was changed according to the 10 set platforms. Simultaneous
blood samples from the jugular bulb and radial artery were taken and analyzed for reference SavO2. Comparing the rSO2 (monitored by the
regional oximeter) to the reference SavO2, the absolute and trend accuracy of the regional oximeter were calculated. Multiple linear regression
analysis was performed on the effects of sex, skin color, and age.
　　Main Results: The bias and standard deviation of absolute accuracy was 0.80% and 2.90%. Trend accuracy analysis yielded a bias of
0.92% with a standard deviation of 2.53%. The root-mean-square accuracy of absolute accuracy (Arms) was 3.00%; the root-mean-square accuracy of trend accuracy (Arms-t) was 2.69%; the Arms and Arms-t under SavO2 ≤ 60% are 2.98% and 2.82%; the Arms and Arms-t under SavO2 > 60%
are 3.01% and 2.55%. Gender, skin color and age did not significantly affect the accuracy (all P > 0.05).
　　Significance: rSO2 readings by Mindray's device and the reusable probe had good absolute and trend accuracies with respect the calculated reference values.
Keywords
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DOI: http://dx.doi.org/10.70711/pmr.v3i11.10330
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