Clinical Characteristics and Prognostic Analysis of Mixed Infections in Children with Mycoplasma Pneumoniae Pneumonia
Abstract
group (n=312) and a mixed infection group (n=174) based on etiology. The clinical characteristics, laboratory indicators, imaging findings,
and outcomes of the two groups were compared, and risk factors were analyzed using multivariable logistic regression. Results: The mixed
infection group had a longer duration of fever and hospitalization compared to the pure group (both P<0.01), with higher rates of severe pneumonia (34.5% vs 15.7%), complications, and antibiotic escalation. The most common pathogens in mixed infections were Streptococcus pneumoniae (23.6%), Haemophilus influenzae (18.4%), and Respiratory Syncytial Virus (14.9%). Age <3 years, antibiotic use before admission,
CRP >40 mg/L, and LDH >360 U/L were identified as independent risk factors. The mixed infection group had prolonged fever resolution
and imaging absorption times, but there was no difference in long-term recurrence rates between the two groups. Conclusion: The incidence
of mixed infections in children with MPP is high, significantly exacerbating the condition and prolonging the course of disease. Early identification of children who are young, have a history of antibiotic use before admission, and have significantly elevated inflammatory markers is
crucial. Timely adjustments to the anti-infective regimen are necessary to improve prognosis.
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DOI: http://dx.doi.org/10.70711/pmr.v3i11.10333
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