Research Progress of Carbonic Anhydrase in Colorectal Cancer
Abstract
been found that the CA family is closely related to the occurrence, diagnosis, treatment and prognosis of colorectal cancer, and CA research
has become a potential direction for cancer treatment. Therefore, we reviewed the research progress of CA isoforms and their role in colorectal cancer.
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[1] XIA C, DONG X, LI H, et al. Cancer statistics in China and United States, 2022: profiles, trends, and determinants[J]. Chin Med J (Engl),
2022, 135(5): 584-590.
[2] DANIL D N A, AL H N, FARHAT S Y. Targeting Colorectal Cancer Cells with a Functionalised Calix[4]arene Receptor: Biophysical
Studies[J]. Molecules, 2022, 27(2).
[3] LI Z, JIANG L, TOYOKUNI S. Role of carbonic anhydrases in ferroptosis-resistance[J]. Arch Biochem Biophys, 2020, 689: 108440.
[4] PENG Y, ZHANG Z, ZHANG A, et al. Membrane-cytoplasm translocation of annexin A4 is involved in the metastasis of colorectal
carcinoma[J]. Aging (Albany NY), 2021, 13(7): 10312-10325.
[5] ZHANG J, TSOI H, LI X, et al. Carbonic anhydrase IV inhibits colon cancer development by inhibiting the Wnt signalling pathway
through targeting the WTAP-WT1-TBL1 axis[J]. Gut, 2016, 65(9): 1482-1493.
[6] UHLEN M, ZHANG C, LEE S, et al. A pathology atlas of the human cancer transcriptome[J]. Science, 2017, 357(6352).
[7] MAURYA N S, KUSHWAHA S, VETUKURI R R, et al. Unlocking the Potential of the CA2, CA7, and ITM2C Gene Signatures for
the Early Detection of Colorectal Cancer: A Comprehensive Analysis of RNA-Seq Data by Utilizing Machine Learning Algorithms[J].
Genes (Basel), 2023, 14(10).
[8] CHOI J H, LEE J, OH J H, et al. Variations in the bitterness perception-related genes TAS2R38 and CA6 modify the risk for colorectal
cancer in Koreans[J]. Oncotarget, 2017, 8(13): 21253-21265.
[9] CICCONE V, FILIPPELLI A, ANGELI A, et al. Pharmacological Inhibition of CA-IX Impairs Tumor Cell Proliferation, Migration and
Invasiveness[J]. Int J Mol Sci, 2020, 21(8).
[10] TAKAHASHI H, SUZUKI Y, NISHIMURA J, et al. Characteristics of carbonic anhydrase 9 expressing cells in human intestinal crypt
base[J]. Int J Oncol, 2016, 48(1): 115-122.
[11] QURESHI-BAIG K, KUHN D, VIRY E, et al. Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway[J]. Autophagy, 2020, 16(8): 1436-1452.
[12] TUPA V, DRAHOSOVA S, GRENDAR M, et al. Expression and association of carbonic anhydrase IX and cyclooxygenase-2 in colorectal cancer[J]. Pathol Res Pract, 2019, 215(4): 705-711.
[13] QI C, HONG L, CHENG Z, et al. Identification of metastasis-associated genes in colorectal cancer using metaDE and survival
analysis[J]. Oncol Lett, 2016, 11(1): 568-574.
[14] ZHOU R, HUANG W, YAO Y, et al. CA II, a potential biomarker by proteomic analysis, exerts significant inhibitory effect on the
growth of colorectal cancer cells[J]. Int J Oncol, 2013, 43(2): 611-621.
[15] TIENG F, ABU N, SUKOR S, et al. L1CAM, CA9, KLK6, HPN, and ALDH1A1 as Potential Serum Markers in Primary and Metastatic
Colorectal Cancer Screening[J]. Diagnostics (Basel), 2020, 10(7).
[16] GUAN S S, WU C T, LIAO T Z, et al. A novel (111)indium-labeled dual carbonic anhydrase 9-targeted probe as a potential SPECT imaging radiotracer for detection of hypoxic colorectal cancer cells[J]. Eur J Pharm Biopharm, 2021, 168: 38-52.
[17] TULUCE Y, AHMED B A, KOYUNCU I, et al. The cytotoxic, apoptotic and oxidative effects of carbonic anhydrase IX inhibitor on
colorectal cancer cells[J]. J Bioenerg Biomembr, 2018, 50(2): 107-116.
[18] SHAMSI F, HASAN P, QUEEN A, et al. Synthesis and SAR studies of novel 1, 2, 4-oxadiazole-sulfonamide based compounds as potential anticancer agents for colorectal cancer therapy[J]. Bioorg Chem, 2020, 98: 103754.
[19] HSIEH M, HUANG P J, CHOU P Y, et al. Carbonic Anhydrase VIII (CAVIII) Gene Mediated Colorectal Cancer Growth and Angiogenesis through Mediated miRNA 16-5p[J]. Biomedicines, 2022, 10(5).
[20] DOYEN J, PARKS S K, MARCIE S, et al. Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells
by increasing intracellular acidosis[J]. Front Oncol, 2012, 2: 199.
[21] YANG G Z, HU L, CAI J, et al. Prognostic value of carbonic anhydrase VII expression in colorectal carcinoma[J]. BMC Cancer, 2015,
15: 209.
[22] BECKER H M, DEITMER J W. Transport Metabolons and Acid/Base Balance in Tumor Cells[J]. Cancers (Basel), 2020, 12(4).
[23] KOVACOVA Z, HODOROVA I. Carbonic Anhydrase IX and Survivin in Colorectal Adenocarcinoma Cells: Slovakian Population
Study[J]. Biology (Basel), 2021, 10(9).
[24] CHEN S H, ZHANG B Y, ZHOU B, et al. Perineural invasion of cancer: a complex crosstalk between cells and molecules in the
perineural niche[J]. Am J Cancer Res, 2019, 9(1): 1-21.
[25] ROTERMUND A, BRANDT S, STAEGE M S, et al. Differential CMS-Related Expression of Cell Surface Carbonic Anhydrases IX and
XII in Colorectal Cancer Models-Implications for Therapy[J]. Int J Mol Sci, 2023, 24(6).
DOI: http://dx.doi.org/10.18686/pmr.v2i2.4445
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