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Geological and Mining Engineering

Geological and Mining Engineering (GME), published by Scineer Publishing PTE. LTD, is an open-access journal. GME is devoted to publish geological and mining engineering related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on geological and mining engineering throughout the world. GME welcomes all original

ISSN: 3029-1887(P)
3029-2034(O)

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Food Safety and Quality


Food Safety and Quality (FSQ), published by Scineer Publishing PTE. LTD, is an open-access journal. FSQ is devoted to publish food safety and quality related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on food safety and quality throughout the world. FSQ welcomes all original manuscripts that do not be published in any other journals.

ISSN: 3029-2115(P)
3029-2123(O)

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Hydraulic Engineering and Power Research

Hydraulic Engineering and Power Research (HEPR), published by Scineer Publishing PTE. LTD, is an open-access journal. HEPR is devoted to publish hydraulic engineering and power related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on hydraulic engineering and power throughout the world. HEPR welcomes all original manuscripts that do not be published in any other journals.Â

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    ISSN: 3029-2158(P)
         3029-2166(O)

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Medical and Health Research

Medical and Health Research (MHR), published by Scineer Publishing PTE. LTD, is an open-access journal. MHR is devoted to publish medicine related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on medicine throughout the world. MHR welcomes all original manuscripts that do not be published in any other journals.Â

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    ISSN: 3029-2190(P)
         3029-2204(O)

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Practical Medical Research

Practical Medical Research (PMR), published by Scineer Publishing PTE. LTD, is an open-access journal. PMR is devoted to publish medicine related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on medicine throughout the world. PMR welcomes all original manuscripts that do not be published in any other journals.Â


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    ISSN: 3029-2085(P)
          3029-2093(O)

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Forum on Research and Innovation Management

Forum on Research and Innovation Management (FRIM), published by Scineer Publishing PTE. LTD, is an open-access journal. FRIM is devoted to publish research and innovation management related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on research and innovation management throughout the world. FRIM welcomes all original manuscripts that do not be published in any other journals.Â

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    ISSN: 3029-1933(P)
         3029-1984(O)

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Construction Safety Technology and Management

Construction Safety Technology and Management (CSTM), published by Scineer Publishing PTE. LTD, is an open-access journal. CSTM is devoted to publish construction safety technology and management related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on construction safety technology and management throughout the world. CSTM welcomes all original manuscripts that do not be published in any other journals.Â

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     ISSN: 3029-2069(P)
           3029-2077(O)

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Industrial Technology Research

Industrial Technology Research (ITR), published by Scineer Publishing PTE. LTD, is an open-access journal. ITR is devoted to publish industrial technology related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on industrial technology throughout the world. ITR welcomes all original manuscripts that do not be published in any other journals.

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    ISSN: 3029-1895(P)
          3029-2026(O)

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Environmental Protection and Health

Environmental Protection and Health (EPH), published by Scineer Publishing PTE. LTD, is an open-access journal. EPH is devoted to publish environmental protection and health related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on environmental protection and health throughout the world. EPH welcomes all original manuscripts that do not be published in any other journals.Â

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    ISSN: 3029-1909(P)
         3029-2018(O)

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Artificial Intelligence Technology Research

Artificial Intelligence Technology Research (AITR), published by Scineer Publishing PTE. LTD, is an open-access journal. AITR is devoted to publish artificial intelligence technology related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on artificial intelligence technology throughout the world. AITR welcomes all original manuscripts that do not be published in any other journals.Â

    ISSN: 3029-1968(O)
         3029-195X(P)
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Curriculum Learning and Exploration

Curriculum Learning and Exploration (CLE), published by Scineer Publishing PTE. LTD, is an open-access journal. CLE is devoted to publish curriculum related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on curriculum throughout the world. CLE welcomes all original manuscripts that do not be published in any other journals.Â

    ISSN: 3029-1976(O)
         3029-1941(P)
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Evaluation of Educational Research

Evaluation of Educational Research (EER), published by Scineer Publishing PTE. LTD, is an open-access journal. EER is devoted to publish education related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on education throughout the world. EER welcomes all original manuscripts that do not be published in any other journals.

    ISSN: 3029-1992(O)
         3029-1925(P)
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World Education Forum

World Education Forum (WEF), published by Scineer Publishing PTE. LTD, is an open-access journal. WEF is devoted to publish education related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on education throughout the world. WEF welcomes all original manuscripts that do not be published in any other journals.

    ISSN: 3029-214X(O)
         3029-2131(P)

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New Explorations in Education and Teaching

New Explorations in Education and Teaching (NEET), published by Scineer Publishing PTE. LTD, is an open-access journal. NEET is devoted to publish education related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on education throughout the world. NEET welcomes all original manuscripts that do not be published in any other journals.Â

    ISSN: 3029-200X(O)
         3029-1917(P)

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Modern Economic Management Forum

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Modern Economic Management Forum (MEMF), published by Scineer Publishing PTE. LTD, is an open-access journal. MEMF is devoted to publish modern economic management related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on economic management throughout the world. MEMF welcomes all original manuscripts that do not be published in any other journals.Â
    ISSN: 3029-2182(O)
         3029-2174(P)

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Research and Commentary on Humanities and Arts

Research and Commentary on Humanities and Arts (RCHA), published by Scineer Publishing PTE. LTD, is an open-access journal. RCHA is devoted to publish humanities and arts related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on humanities and arts throughout the world. RCHA welcomes all original manuscripts that do not be published in any other journals.Â

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      ISSN: 3029-2050(O)
           3029-2042(P)

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Research Progress of Carbonic Anhydrase in Colorectal Cancer

Minhong Zou, Shipeng Lu, Ya Peng*

Abstract


Carbonic anhydrase (CA) is an important group of proteins involved in the survival, invasion, and metastasis of solid cancers. It has
been found that the CA family is closely related to the occurrence, diagnosis, treatment and prognosis of colorectal cancer, and CA research
has become a potential direction for cancer treatment. Therefore, we reviewed the research progress of CA isoforms and their role in colorectal cancer.

Keywords


Carbonic anhydrase; Colorectal cancer; Occurrence; Diagnosis; Treatment; Prognosis

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References


[1] XIA C, DONG X, LI H, et al. Cancer statistics in China and United States, 2022: profiles, trends, and determinants[J]. Chin Med J (Engl),

2022, 135(5): 584-590.

[2] DANIL D N A, AL H N, FARHAT S Y. Targeting Colorectal Cancer Cells with a Functionalised Calix[4]arene Receptor: Biophysical

Studies[J]. Molecules, 2022, 27(2).

[3] LI Z, JIANG L, TOYOKUNI S. Role of carbonic anhydrases in ferroptosis-resistance[J]. Arch Biochem Biophys, 2020, 689: 108440.

[4] PENG Y, ZHANG Z, ZHANG A, et al. Membrane-cytoplasm translocation of annexin A4 is involved in the metastasis of colorectal

carcinoma[J]. Aging (Albany NY), 2021, 13(7): 10312-10325.

[5] ZHANG J, TSOI H, LI X, et al. Carbonic anhydrase IV inhibits colon cancer development by inhibiting the Wnt signalling pathway

through targeting the WTAP-WT1-TBL1 axis[J]. Gut, 2016, 65(9): 1482-1493.

[6] UHLEN M, ZHANG C, LEE S, et al. A pathology atlas of the human cancer transcriptome[J]. Science, 2017, 357(6352).

[7] MAURYA N S, KUSHWAHA S, VETUKURI R R, et al. Unlocking the Potential of the CA2, CA7, and ITM2C Gene Signatures for

the Early Detection of Colorectal Cancer: A Comprehensive Analysis of RNA-Seq Data by Utilizing Machine Learning Algorithms[J].

Genes (Basel), 2023, 14(10).

[8] CHOI J H, LEE J, OH J H, et al. Variations in the bitterness perception-related genes TAS2R38 and CA6 modify the risk for colorectal

cancer in Koreans[J]. Oncotarget, 2017, 8(13): 21253-21265.

[9] CICCONE V, FILIPPELLI A, ANGELI A, et al. Pharmacological Inhibition of CA-IX Impairs Tumor Cell Proliferation, Migration and

Invasiveness[J]. Int J Mol Sci, 2020, 21(8).

[10] TAKAHASHI H, SUZUKI Y, NISHIMURA J, et al. Characteristics of carbonic anhydrase 9 expressing cells in human intestinal crypt

base[J]. Int J Oncol, 2016, 48(1): 115-122.

[11] QURESHI-BAIG K, KUHN D, VIRY E, et al. Hypoxia-induced autophagy drives colorectal cancer initiation and progression by activating the PRKC/PKC-EZR (ezrin) pathway[J]. Autophagy, 2020, 16(8): 1436-1452.

[12] TUPA V, DRAHOSOVA S, GRENDAR M, et al. Expression and association of carbonic anhydrase IX and cyclooxygenase-2 in colorectal cancer[J]. Pathol Res Pract, 2019, 215(4): 705-711.

[13] QI C, HONG L, CHENG Z, et al. Identification of metastasis-associated genes in colorectal cancer using metaDE and survival

analysis[J]. Oncol Lett, 2016, 11(1): 568-574.

[14] ZHOU R, HUANG W, YAO Y, et al. CA II, a potential biomarker by proteomic analysis, exerts significant inhibitory effect on the

growth of colorectal cancer cells[J]. Int J Oncol, 2013, 43(2): 611-621.

[15] TIENG F, ABU N, SUKOR S, et al. L1CAM, CA9, KLK6, HPN, and ALDH1A1 as Potential Serum Markers in Primary and Metastatic

Colorectal Cancer Screening[J]. Diagnostics (Basel), 2020, 10(7).

[16] GUAN S S, WU C T, LIAO T Z, et al. A novel (111)indium-labeled dual carbonic anhydrase 9-targeted probe as a potential SPECT imaging radiotracer for detection of hypoxic colorectal cancer cells[J]. Eur J Pharm Biopharm, 2021, 168: 38-52.

[17] TULUCE Y, AHMED B A, KOYUNCU I, et al. The cytotoxic, apoptotic and oxidative effects of carbonic anhydrase IX inhibitor on

colorectal cancer cells[J]. J Bioenerg Biomembr, 2018, 50(2): 107-116.

[18] SHAMSI F, HASAN P, QUEEN A, et al. Synthesis and SAR studies of novel 1, 2, 4-oxadiazole-sulfonamide based compounds as potential anticancer agents for colorectal cancer therapy[J]. Bioorg Chem, 2020, 98: 103754.

[19] HSIEH M, HUANG P J, CHOU P Y, et al. Carbonic Anhydrase VIII (CAVIII) Gene Mediated Colorectal Cancer Growth and Angiogenesis through Mediated miRNA 16-5p[J]. Biomedicines, 2022, 10(5).

[20] DOYEN J, PARKS S K, MARCIE S, et al. Knock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells

by increasing intracellular acidosis[J]. Front Oncol, 2012, 2: 199.

[21] YANG G Z, HU L, CAI J, et al. Prognostic value of carbonic anhydrase VII expression in colorectal carcinoma[J]. BMC Cancer, 2015,

15: 209.

[22] BECKER H M, DEITMER J W. Transport Metabolons and Acid/Base Balance in Tumor Cells[J]. Cancers (Basel), 2020, 12(4).

[23] KOVACOVA Z, HODOROVA I. Carbonic Anhydrase IX and Survivin in Colorectal Adenocarcinoma Cells: Slovakian Population

Study[J]. Biology (Basel), 2021, 10(9).

[24] CHEN S H, ZHANG B Y, ZHOU B, et al. Perineural invasion of cancer: a complex crosstalk between cells and molecules in the

perineural niche[J]. Am J Cancer Res, 2019, 9(1): 1-21.

[25] ROTERMUND A, BRANDT S, STAEGE M S, et al. Differential CMS-Related Expression of Cell Surface Carbonic Anhydrases IX and

XII in Colorectal Cancer Models-Implications for Therapy[J]. Int J Mol Sci, 2023, 24(6).




DOI: http://dx.doi.org/10.18686/pmr.v2i2.4445

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