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Geological and Mining Engineering

Geological and Mining Engineering (GME), published by Scineer Publishing PTE. LTD, is an open-access journal. GME is devoted to publish geological and mining engineering related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on geological and mining engineering throughout the world. GME welcomes all original

ISSN: 3029-1887(P)

3029-2034(O)

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Food Safety and Quality

Food Safety and Quality (FSQ), published by Scineer Publishing PTE. LTD, is an open-access journal. FSQ is devoted to publish food safety and quality related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on food safety and quality throughout the world. FSQ welcomes all original manuscripts that do not be published in any other journals.

ISSN: 3029-2115(P)

3029-2123(O)

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Hydraulic Engineering and Power Research

Hydraulic Engineering and Power Research (HEPR), published by Scineer Publishing PTE. LTD, is an open-access journal. HEPR is devoted to publish hydraulic engineering and power related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on hydraulic engineering and power throughout the world. HEPR welcomes all original manuscripts that do not be published in any other journals.Â

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Â Â Â Â ISSN: 3029-2158(P)

Â Â Â Â Â Â Â Â Â 3029-2166(O)

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Medical and Health Research

Medical and Health Research (MHR), published by Scineer Publishing PTE. LTD, is an open-access journal. MHR is devoted to publish medicine related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on medicine throughout the world. MHR welcomes all original manuscripts that do not be published in any other journals.Â

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Â Â Â Â ISSN: 3029-2190(P)

Â Â Â Â Â Â Â Â Â 3029-2204(O)

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Practical Medical Research

Practical Medical Research (PMR), published by Scineer Publishing PTE. LTD, is an open-access journal. PMR is devoted to publish medicine related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on medicine throughout the world. PMR welcomes all original manuscripts that do not be published in any other journals.Â

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Â Â Â Â ISSN: 3029-2085(P)

Â Â Â Â Â Â Â Â Â Â 3029-2093(O)

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Forum on Research and Innovation Management

Forum on Research and Innovation Management (FRIM), published by Scineer Publishing PTE. LTD, is an open-access journal. FRIM is devoted to publish research and innovation management related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on research and innovation management throughout the world. FRIM welcomes all original manuscripts that do not be published in any other journals.Â

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Â Â Â Â ISSN: 3029-1933(P)

Â Â Â Â Â Â Â Â Â 3029-1984(O)

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Construction Safety Technology and Management

Construction Safety Technology and Management (CSTM), published by Scineer Publishing PTE. LTD, is an open-access journal. CSTM is devoted to publish construction safety technology and management related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on construction safety technology and management throughout the world. CSTM welcomes all original manuscripts that do not be published in any other journals.Â

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Â Â Â Â Â ISSN: 3029-2069(P)

Â Â Â Â Â Â Â Â Â Â Â 3029-2077(O)

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Industrial Technology Research

Industrial Technology Research (ITR), published by Scineer Publishing PTE. LTD, is an open-access journal. ITR is devoted to publish industrial technology related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on industrial technology throughout the world. ITR welcomes all original manuscripts that do not be published in any other journals.

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Â Â Â Â ISSN: 3029-1895(P)

Â Â Â Â Â Â Â Â Â Â 3029-2026(O)

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Environmental Protection and Health

Environmental Protection and Health (EPH), published by Scineer Publishing PTE. LTD, is an open-access journal. EPH is devoted to publish environmental protection and health related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on environmental protection and health throughout the world. EPH welcomes all original manuscripts that do not be published in any other journals.Â

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Â Â Â Â ISSN: 3029-1909(P)

Â Â Â Â Â Â Â Â Â 3029-2018(O)

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Artificial Intelligence Technology Research

Artificial Intelligence Technology Research (AITR), published by Scineer Publishing PTE. LTD, is an open-access journal. AITR is devoted to publish artificial intelligence technology related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on artificial intelligence technology throughout the world. AITR welcomes all original manuscripts that do not be published in any other journals.Â

Â Â Â Â ISSN: 3029-1968(O)

Â Â Â Â Â Â Â Â Â 3029-195X(P)
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Curriculum Learning and Exploration

Curriculum Learning and Exploration (CLE), published by Scineer Publishing PTE. LTD, is an open-access journal. CLE is devoted to publish curriculum related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on curriculum throughout the world. CLE welcomes all original manuscripts that do not be published in any other journals.Â

Â Â Â Â ISSN: 3029-1976(O)

Â Â Â Â Â Â Â Â Â 3029-1941(P)
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Evaluation of Educational Research

Evaluation of Educational Research (EER), published by Scineer Publishing PTE. LTD, is an open-access journal. EER is devoted to publish education related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on education throughout the world. EER welcomes all original manuscripts that do not be published in any other journals.

Â Â Â Â ISSN: 3029-1992(O)

Â Â Â Â Â Â Â Â Â 3029-1925(P)
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World Education Forum

World Education Forum (WEF), published by Scineer Publishing PTE. LTD, is an open-access journal. WEF is devoted to publish education related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on education throughout the world. WEF welcomes all original manuscripts that do not be published in any other journals.

Â Â Â Â ISSN: 3029-214X(O)

Â Â Â Â Â Â Â Â Â 3029-2131(P)

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New Explorations in Education and Teaching

New Explorations in Education and Teaching (NEET), published by Scineer Publishing PTE. LTD, is an open-access journal. NEET is devoted to publish education related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on education throughout the world. NEET welcomes all original manuscripts that do not be published in any other journals.Â

Â Â Â Â ISSN: 3029-200X(O)

Â Â Â Â Â Â Â Â Â 3029-1917(P)

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Modern Economic Management Forum

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Modern Economic Management Forum (MEMF), published by Scineer Publishing PTE. LTD, is an open-access journal. MEMF is devoted to publish modern economic management related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on economic management throughout the world. MEMF welcomes all original manuscripts that do not be published in any other journals.Â

Â Â Â Â ISSN: 3029-2182(O)

Â Â Â Â Â Â Â Â Â 3029-2174(P)

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Research and Commentary on Humanities and Arts

Research and Commentary on Humanities and ArtsÂ (RCHA), published by Scineer Publishing PTE. LTD, is an open-access journal. RCHA is devoted to publish humanities and arts related articles in the form of original papers, review papers and case studies. It also provides a platform for scholars to exchange the latest information in the related fields and aim to promote the research on humanities and arts throughout the world. RCHA welcomes all original manuscripts that do not be published in any other journals.Â

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Â Â Â Â Â Â ISSN: 3029-2050(O)

Â Â Â Â Â Â Â Â Â Â Â 3029-2042(P)

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Scineer Publishing is a publisher of open access journals. Covering various disciplines and promoting interdisciplinary development, Scineer Publishing adheres to a principle of respecting academics, and publishes insightful and rigorous academic research contents.

12 Eu Tong Sen Street, #07-168, Singapore 059819

E-mail: scineerpub@126.com

Copyright © 2023 Scineer Publishing Pte. Ltd.

Current Status of Transfer RNA-derived Small RNAs in Cancers

Yuting Luo, Hehua Hu, Jiayi Chen*

Abstract

Transfer RNA-derived small RNAs (tsRNAs) are a new type of non-coding small RNAs produced by the processing and splicing
of precursor or mature transfer RNAs by specific endonucleases under unfavorable conditions, such as starvation, oxidative stress, hypoxia,
etc. tsRNAs have been found to be abnormally expressed in multiple types of cancers. With the development of science and technology, their
regulatory mechanisms have been gradually discovered. This review summarizes the progress of tsRNAs in cancers of gastrointestinal system,
breast system and reproductive system, and lays the foundation for the diagnosis and treatment of the diseases.

Keywords

tsRNA; Cancers; Disease; Biomarker

Full Text:

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References

[1] Mikhail G D, Cory B G, Kristi A K, Jonathan D W: Systematic classification of non-coding RNAs by epigenomic similarity. BMC

Bioinformatics 2013(0).

[2] A Gregory M, Rebecca M T, Michael P T: Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs. Nat Rev

Mol Cell Biol 2007, 8(3).

[3] Phuong T B H, Ian M C, Linh T T L: MicroRNA-Based Diagnosis and Therapy. Int J Mol Sci 2022, 23(13).

[4] Xin W, Anne R, Martine S, Mo-Fang L: Emerging roles and functional mechanisms of PIWI-interacting RNAs. Nat Rev Mol Cell

Biol, 24(2).

[5] Yang J, Wei T, Yedi Z: Transfer RNA-derived small RNAs: potential applications as novel biomarkers for disease diagnosis and

prognosis. Ann Transl Med 2020, 8(17).

[6] Aleksej D, Vera O, Conor T, Eva J, Dorothea A, Markus H, Steffen K, Stefanie K, Matthias R S: Production and purification of endogenously modified tRNA-derived small RNAs. RNA Biol 2020, 17(8).

[7] Lin X, Jie W, Shaoqing J, Ming C, Rongrong J: Disorders and roles of tsRNA, snoRNA, snRNA and piRNA in cancer. J Med Genet

2022, 59(7).

[8] Fangfang J, Liuqing Y, Weixiang W, Na Y, Shoubin Z, Ping Y, Xi C, Tonghui M, Yanbo W: A novel class of tsRNA signatures as biomarkers for diagnosis and prognosis of pancreatic cancer. Mol Cancer 2021, 20(1).

[9] Ting H, Yuexin Z, Guoqin J, Zhixue Y: tsRNA: A Promising Biomarker in Breast Cancer. J Cancer 2024, 15(9).

[10] Alison P K: Pancreatic cancer epidemiology: understanding the role of lifestyle and inherited risk factors. Nat Rev Gastroenterol

Hepatol 2021, 18(7).

[11] Lei J, Chunfu Z, Xihu Q: Expression profile of tRNA-derived fragments in pancreatic cancer. Oncol Lett 2019, 18(3).

[12] Parisa K, Farhad I, Sharmila A, Neal D F, Farin K: Gastric cancer: descriptive epidemiology, risk factors, screening, and prevention. Cancer Epidemiol Biomarkers Prev 2014, 23(5).

[13] Jing X, Yue W, Xian L, Ming Z, Yang L, Weiwei Z: Clinical value assessment for serum hsa_tsr013526 in the diagnosis of gastric

carcinoma. Environ Toxicol 2024, 39(5).

[14] Xun L, Yu Z, Yang L, Xinliang G, Shaoqing J: A comprehensive evaluation of serum tRF-29-R9J8909NF5JP as a novel diagnostic

and prognostic biomarker for gastric cancer. Mol Carcinog 2023, 62(10).

[15] Yijing S, Xiuchong Y, Yao R, Zhe L, Yaoyao X, Zhilong Y, Junming G: Global profile of tRNA-derived small RNAs in gastric cancer

patient plasma and identification of tRF-33-P4R8YP9LON4VDP as a new tumor suppressor. Int J Med Sci 2021, 18(7).

[16] Muhammad A, Mehwish I, Muhammad D, Asmat Ullah K: Awareness and current knowledge of breast cancer. Biol Res 2017, 50(1).

[17] Jingyi W, Ge M, Han G, Xu H, Xinrui M, Xinyang W, Jordee Selvamanee V, Tiansong X, Xiaoan L, Shui W: Circulating tRNAderived small RNAs (tsRNAs) signature for the diagnosis and prognosis of breast cancer. NPJ Breast Cancer 2021, 7(1).

[18] Jun Z, Fang W, Yike W, Jinpei L, Xuan Z: Small RNA sequencing reveals a novel tsRNA-26576 mediating tumorigenesis of breast

cancer. Cancer Manag Res 2019, 11(0).

[19] Stephanie L, Marsela B, Amit M O: Epithelial ovarian cancer: Evolution of management in the era of precision medicine. CA Cancer J Clin 2019, 69(4).

[20] Eric Y P, Yang S, Yuke W, Feier Z, Shuangyan T, Yun D, Yiqi D, Haining C, Lei Z, Heng X: Presence and diagnostic value of circulating tsncRNA for ovarian tumor. Mol Cancer 2018, 17(1).

[21] Konstantina P, Paraskevi M, Tobias D, Julia D, Eva O, Sven M, Toon vG, Ioana B, Viktor M, Robert Z et al: tRNA-derived small RNA

3'U-tRF(ValCAC) promotes tumour migration and early progression in ovarian cancer. Eur J Cancer 2023, 180(0).

[22] Menghong Y, Qiwei Z: Sperm tsRNAs and acquired metabolic disorders. J Endocrinol 2016, 230(3).

[23] Qiuyan W, Yao W, Yaoyao X, Xiuchong Y, Shuangshuang Z, Jiaxin G, Zhe L, Guoliang Y, Junming G: Extracellular vesicles-associated tRNA-derived fragments (tRFs): biogenesis, biological functions, and their role as potential biomarkers in human diseases. J

Mol Med (Berl) 2022, 100(5).

DOI: http://dx.doi.org/10.18686/pmr.v2i2.4446

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Scineer Publishing is a publisher of open access journals. Covering various disciplines and promoting interdisciplinary development, Scineer Publishing adheres to a principle of respecting academics, and publishes insightful and rigorous academic research contents.

12 Eu Tong Sen Street, #07-168, Singapore 059819

E-mail: scineerpub@126.com

Copyright © 2023 Scineer Publishing Pte. Ltd.