pisco_log
banner

Review on Research Progress of Puerarin in the Treatment of Diabetes

Xuyuan Zhang, Meihong Ge, Shenjia Qiu

Abstract


Puerarin is one of the main active ingredients in Chinese herbal medicine puerarin. In recent years, it has been found that puerarin
has a good therapeutic effect in the treatment of diabetes. It has been found that puerarin can promote the proliferation of islet beta cells, improve insulin resistance and delay the progression of diabetes complications. This paper reviews the literatures on puerarin in the treatment of
diabetes in recent years, and summarizes the ways of puerarin in the treatment of diabetes, in order to provide theoretical support for puerarin
in the treatment of diabetes.

Keywords


Puerarin; Diabetes mellitus; Insulin

Full Text:

PDF

Included Database


References


[1] Chen M. Effects of puerarin on mitochondrial oxidative stress damage of type 2 diabetic islet beta cells via miR-124a and its mechanism

[D]. Nanning: Guangxi Medical University, 2022.

[2] Yang Lei, Shu Yu, Yao Dongdong, et al. On the protective effect of puerarin on ? cells [J]. Chinese Journal of Traditional Chinese Medicine, 2014, 29 (11): 3488-3490.

[3] Bai Jichang, Tan Lixin, Liu Zanchao, et al. Effect of puerarin on insulin resistance in 3T3-L1 adipocytes and its mechanism [J]. Journal

of Guangxi Medical University, 2024, 41 (01): 40-45.

[4] Su Qingya, Zhang Xin, Liao Qixin, et al. Progress in puerarin for type 2 diabetes mellitus and its complications [J]. Journal of Guizhou

University of Traditional Chinese Medicine, 2024, 46 (02): 70-76.

[5] Song Chong, Du Qing, and Li Xinliang. Protective effects of puerarin on D-galactose-induced heart in aging mice [J]. Chinese Journal

of Basic Medicine of Traditional Chinese Medicine, 2024, 30 (01): 35-40.

[6] Qin W, Guo J, Gou W, et al. Molecular mechanisms of isoflavone puerarin against cardiovascular diseases: What we know and where

we go[J]. Chinese Herbal Medicines, 2022, 14 (02): 234-243.

[7] Zhou Yunsong, Zhao Qi, Hu Fang, et al. Puerarin improved ketoconazole-induced liver injury in rats by inhibiting the AHR / oxidative

stress pathway study [J]. Journal of Practical Liver Diseases, 2024, 27 (05): 669-672.

[8] Zhang Tongcui, Yao Ruojin, Wang Chao, et al. The protective effect of puerarin on non-alcoholic fatty liver disease in mice [J]. Biotechnology Progress, 2024, 14 (03): 480-485.

[9] Guo Jingjing, Zhang Wenlong, Liang Piao, et al. Puerarin alleviates LPS-induced acute kidney injury in mice: based on regulation of

SIRT1/NF-?B signaling pathway [J]. Journal of Southern Medical University, 2023, 43 (07): 1248-1253.




DOI: http://dx.doi.org/10.70711/pmr.v2i3.5460

Refbacks

  • There are currently no refbacks.