Dose-Effect Analysis of Esketamine Combined with Sufentanil in Postoperative Pain Management after Laparoscopic Cholecystectomy and Its Impact on Quality of Life
Abstract
Objective: To evaluate and compare the dose-effect of esketamine and sufentanil during the induction phase of general anesthesia
on postoperative pain management after thoracoscopy surgery and their impact on the quality of recovery. Methods: A total of 80 patients,
aged 25 to 60, undergoing thoracoscopy surgery under general anesthesia were randomly assigned to two groups: the esketamine group (Group
A) and the sufentanil group (Group B), with 40 cases in each group. Results: Intraoperatively, there were no significant differences in mean
arterial pressure (MAP) and heart rate (HR) between the two groups at time points T0 to T5 (P > 0.05). Compared with the baseline values,
both groups decreased at T2, with Group B being closer to the baseline values; at T3, both groups showed a transient increase, with Group
B being closer to the baseline values.Postoperatively, the times of the analgesic pump was pressed was also significantly reduced (P < 0.05).
Conclusion: Compared with sufentanil, the use of esketamine during the induction phase of general anesthesia in patients surgery can effectively alleviate postoperative pain and is worth promoting and applying in clinical practice.
on postoperative pain management after thoracoscopy surgery and their impact on the quality of recovery. Methods: A total of 80 patients,
aged 25 to 60, undergoing thoracoscopy surgery under general anesthesia were randomly assigned to two groups: the esketamine group (Group
A) and the sufentanil group (Group B), with 40 cases in each group. Results: Intraoperatively, there were no significant differences in mean
arterial pressure (MAP) and heart rate (HR) between the two groups at time points T0 to T5 (P > 0.05). Compared with the baseline values,
both groups decreased at T2, with Group B being closer to the baseline values; at T3, both groups showed a transient increase, with Group
B being closer to the baseline values.Postoperatively, the times of the analgesic pump was pressed was also significantly reduced (P < 0.05).
Conclusion: Compared with sufentanil, the use of esketamine during the induction phase of general anesthesia in patients surgery can effectively alleviate postoperative pain and is worth promoting and applying in clinical practice.
Keywords
Esketamine; Sufentanil; Laparoscopic Cholecystectomy; Pain; Dose-Effect; Quality of Life
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PDFReferences
[1] Li Tongzhou. The Impact of Esketamine on Hemodynamics and Stress Response in Patients Undergoing Laparoscopic Cholecystectomy
[D]. North China University of Science and Technology, 2023.
[2] Yang Lijuan, Chen Jun, Luo Yun, Ren Zhendong, Cui Yongliang, Luo Zili. Observation on the Effect of Esketamine Combined with
Sufentanil for Postoperative Pain Relief after Laparoscopic Hysterectomy [J]. Frontiers of Medicine, 2023, 13(15): 84-86.
[3] Li Mengtao. The Impact of Esketamine on Early Cognitive Function in Elderly Patients Undergoing Laparoscopic Cholecystectomy [D].
Hebei Medical University, 2023.
DOI: http://dx.doi.org/10.70711/pmr.v2i3.5462
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