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Study on the Effects of Soluble Transferrin Receptor on Iron Metabolism in Patients with Pancytopenia

Haige Zhao, Jing Wang, Jingping Ran, Mengyao Xiao, Xiaoman Lyu

Abstract


This study investigates the effects of soluble transferrin receptor (sTfR) on iron metabolism in patients with pancytopenia. By
analyzing the biological characteristics of sTfR, it elucidates its key role in iron metabolism regulation. The research finds that sTfR is not
only a sensitive marker for functional iron deficiency but also has unique value in early diagnosis and differential diagnosis, accurately reflecting the iron requirement status in pancytopenia patients. Results show that dynamic monitoring of sTfR levels has significant clinical
implications for guiding treatment plan adjustments and prognosis assessment, providing scientific basis for the diagnosis and treatment of
related diseases.

Keywords


Soluble transferrin receptor; Pancytopenia; Iron metabolism; Early diagnosis; Differential diagnosis

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References


[1] Hou L, Xu E, Xia L, et al. Application of Iron Metabolism-Related Biochemical Indicators in Iron Deficiency Anemia Diagnosis [J].

Chinese Journal of Laboratory Diagnosis, 2022(5):45-46.

[2] Zhong G, Hu P. Correlation between Serum Hepcidin, Transferrin Receptor Levels and Iron Deficiency, Micro-inflammatory Response

in Hemodialysis Patients [J]. Journal of Hainan Medical University, 2017(12):130-132.

[3] Zhou S, Du J, Li Y, et al. Diagnostic Value of Soluble Transferrin Receptor, Membrane Iron Transport Protein 1, and Hepcidin in Iron

Deficiency Anemia during Pregnancy [J]. Labeled Immunoassays and Clinical Medicine, 2019(2):26-27.




DOI: http://dx.doi.org/10.70711/pmr.v2i4.6112

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