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Advances in Liquid Biopsy for Early Screening and Monitoring of Gastrointestinal Cancers

Huifen Wu, Yueyue Lu*

Abstract


This review summarizes recent advances in liquid biopsy for early detection and monitoring of gastrointestinal cancers, focusing
on non-invasive biomarkers such as ctDNA, CTCs, exosomes, and miRNAs. These biomarkers show promise in improving early diagnosis,
tracking treatment response, and detecting recurrence. While ctDNA enables real-time monitoring, CTCs and exosomal miRNAs help reveal
tumor dynamics. Despite its potential, challenges like low biomarker levels in early stages and lack of standardization limit clinical application. Further technological development and protocol refinement are needed to fully realize its value in personalized cancer management.

Keywords


Gastrointestinal Cancers; Early Screening; Liquid Biopsy

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References


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DOI: http://dx.doi.org/10.70711/pmr.v2i6.7253

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