Efficacy Observation of Micrograft Transplantation Combined with NB-UVB in the Treatment of Stable Disseminated Vitiligo
Abstract
of stable disseminated vitiligo and its impact on the quality of life of patients. Methods: Sixty-four patients with stable disseminated vitiligo
treated in Chengdu Borun Vitiligo Hospital from March 2021 to March 2023 were selected. They were randomly divided into the treatment group
and the control group by using the random number generator of SPSS 22.0 statistical software. The control group was treated with micrograft
transplantation, while the treatment group was treated with micrograft transplantation combined with NB-UVB. The efficacy of the two groups at
the 12th week of treatment was compared, as well as the Vitiligo Area Scoring Index (VASI) scores and Dermatology Life Quality Index (DLQI)
scores before treatment and at the 4th, 8th, and 12th weeks of treatment. Adverse reactions were recorded during the follow-up until the 12th
week. Results: The total effective rate of the treatment group at the 12th week of treatment was higher than that of the control group (P<0.05).
The VASI scores of both groups at the 4th, 8th, and 12th weeks of treatment were lower than those before treatment (P<0.05), and there were significant differences in the VASI scores between the treatment group and the control group at the 4th, 8th, and 12th weeks of treatment (P<0.05).
The DLQI scores of both groups were lower than those before treatment (P<0.05), and the DLQI scores of the treatment group at the 4th, 8th, and
12th weeks of treatment were lower than those of the control group (P<0.05). There was no significant difference in adverse reactions between the
two groups (P>0.05). Conclusion: Micrograft transplantation combined with NB-UVB has a certain therapeutic effect in the treatment of stable
disseminated vitiligo, with uniform repigmentation, and can improve the quality of life of patients, which is worthy of promotion.
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DOI: http://dx.doi.org/10.70711/pmr.v2i7.7717
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