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The Effect of Endometrial Peristaltic Waves on the Pregnancy Outcome of Natural Cycle Thawed Embryo Transfer

Xiaohong Wang, Fangfang Mei, Yuling Xie, Dantong Wang, Shaoe Huang, Liyun Wang*

Abstract


Objective: To explore the effect of transvaginal ultrasound detection of endometrial peristaltic waves on pregnancy outcomes in patients undergoing natural cycle thawed embryo transfer on the day of endometrial transformation and embryo transfer. Method: From January
2021 to December 2024, 200 cycles of infertile patients who underwent natural cycle thawing embryo transfer at our Huadu District Maternal
and Child Health Hospital (Huzhong Hospital) in Guangzhou were analyzed. According to the pregnancy outcome, they were divided into a
pregnant group and a non pregnant group. The endometrial thickness, morphology, blood flow, and peristalsis parameters on the day of endometrial transformation and embryo transfer were compared between the two groups of patients. The results showed that there was a statistically significant difference in endometrial peristalsis between the two groups on the day of endometrial transformation (P<0.05). The clinical
pregnancy rates without peristaltic waves, with peristaltic waves<3 times/minute, and with peristaltic waves ? 3 times/minute were 64.86%,
65.96%, and 43.90%, respectively. There was a statistically significant difference in endometrial peristalsis between the two groups on the day
of embryo transfer, with clinical pregnancy rates of 65.03%, 42.86%, and 33.33% for those without peristaltic waves, with peristaltic waves<3
times/minute, and with peristaltic waves ? 3 times/minute, respectively. There was no statistically significant difference in endometrial thickness, morphology, and endometrial blood flow classification between the two groups (P>0.05). Conclusion: Transvaginal ultrasound detection
of endometrial peristaltic waves may have significance in predicting the pregnancy outcome of frozen thawed embryo transfer on the day of
endometrial transformation and embryo transfer. Endometrial peristaltic waves ? 3 times/minute reduce the clinical pregnancy rate of thawed
embryo transfer.

Keywords


Endometrial peristalsis; Freeze thawed embryos; Natural cycle; Pregnancy outcome

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References


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DOI: http://dx.doi.org/10.70711/pmr.v3i2.8394

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