Chitosan-Based Hydrogel Dressings for Infected Wound 
Treatment

Xiaojie Liu; Min Liu*

doi:10.70711/pmr.v3i3.8634

Chitosan-Based Hydrogel Dressings for Infected Wound Treatment

Xiaojie Liu, Min Liu*

Abstract

Skin trauma severely impacts patients' quality of life, and its repair process often faces challenges such as long duration, susceptibility to infection, and high recurrence rates, constituting a significant global public health concern. Hydrogels, characterized by their threedimensional network structure and high water content, have emerged as a research hotspot for functional wound dressings due to their excellent softness, good biocompatibility, and high tunability. Chitosan is extensively used in antibacterial materials, primarily owing to its inherent
antimicrobial properties and excellent biocompatibility. This article systematically summarizes recent advances in antibacterial hydrogels
based on chitosan derivatives for wound repair. It focuses on discussing the design and functionalization strategies of chitosan-based hydrogels,
including photothermal therapy, photodynamic therapy, and their integration with monitoring technologies. Furthermore, it explores the opportunities and challenges in their clinical translation, aiming to provide references and insights for developing novel wound management strategies.

Keywords

Nanocomposite Hydrogel; Chitosan-Based Hydrogel; Antibacterial hydrogels; Wound dressing

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References

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DOI: http://dx.doi.org/10.70711/pmr.v3i3.8634

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