Progress in Traditional Chinese Medicine Treatment Principles and Pharmacological Research on Atherosclerosis
Abstract
and increased risks of stroke and myocardial infarction. Although Western drugs such as statins reduce LDL and slow disease progression,
their effectiveness in complex AS and associated side effects remain limiting. In contrast, Traditional Chinese Medicine (TCM) applies a holistic, syndrome-based approach with multi-target advantages. This review summarises TCM perspectives on AS pathogenesis and treatment,
focusing on tonifying the kidney, boosting qi, resolving phlegm, and activating blood to improve symptoms and prognosis. TCM interventions
regulate immunity, oxidative stress, lipid metabolism, and endothelial function, and many formulas show beneficial pharmacological effects.
Further studies are needed to confirm their mechanisms and clinical efficacy.
Keywords
Full Text:
PDFReferences
[1] Pedro-Botet, J., Climent, E., and Benaiges, D. "LDL Cholesterol as a Causal Agent of Atherosclerosis." Clnica e Investigacin en Arteriosclerosis, vol. 36, Suppl. 1, 2024, pp. S3S8.
[2] Wu, Y. R., Xu, Y. Z., and Xu, L. H. "Pharmacological Therapy Targeting the Immune Response in Atherosclerosis." International Immunopharmacology, vol. 141, 2024, p. 112974.
[3] Vergallo, R., and Crea, F. "Atherosclerotic Plaque Healing." New England Journal of Medicine, vol. 383, no. 9, 2020, pp. 846857.
[4] Saglietto, A., Manfredi, R., Elia, E., et al. "Cardiovascular Disease Burden: Italian and Global Perspectives." Minerva Cardiology and
Angiology, vol. 69, no. 3, 2021, pp. 231240.
[5] Vaduganathan, M., Mensah, G. A., Turco, J. V., et al. "The Global Burden of Cardiovascular Diseases and Risk." Journal of the American College of Cardiology, vol. 80, no. 25, 2022, pp. 23612371.
[6] Joseph, P., and Yusuf, S. "Coordinating Efforts to Reduce the Global Incidence of Cardiovascular Disease." New England Journal of
Medicine, vol. 389, no. 14, 2023, pp. 13291331.
[7] Martin, S. S., Aday, A. W., Almarzooq, Z. I., et al. "2024 Heart Disease and Stroke Statistics: A Report of US and Global Data from the
American Heart Association." Circulation, vol. 149, no. 8, 2024, pp. e347e913.
[8] Madaudo, C., Coppola, G., Parlati, A. L. M., et al. "Discovering Inflammation in Atherosclerosis: Insights from Pathogenic Pathways to
Clinical Practice." International Journal of Molecular Sciences, vol. 25, no. 11, 2024, p. 6016.
[9] Qin, Y., Huo, S., Gonzlez, A. M., Guo, L., Sanots, J., & Li, L. (2025).
Research on neuroimmune gastrointestinal diseases based on artificial intelligence: Molecular dynamics analysis of caffeine and DRD3 protein. Current Pharmaceutical Biotechnology. Advance online publication.https://doi.org/10.2174/0113892010325902241120111429
[10] Qin, Y., Feng, J., Wang, T., & Li, L. (2024). New approaches to improve rectal cancer therapy with MC1-1 inhibitors, Bax apoptosis
protein agonists, and oxitinib: Concept of medical intelligence and deep learn. In Proceedings of the 2024 8th International Conference
on Control Engineering and Artificial Intelligence (CCEAI '24) (pp. 1320). ACM. https://doi.org/10.1145/3640824.3640827
[11] Li, L., Jiang, J., Guo, L., Santos, J., Gonzlez, A. M., Li, S., & Qin, Y. (2025). Clinical diagnosis and treatment system for neurological
psychological gastrointestinal diseases based on multimodal artificial intelligence and immunology. Current Pharmaceutical Biotechnology. Advance online publication. https://doi.org/10.2174/0113892010359130250413024112
DOI: http://dx.doi.org/10.70711/pmr.v3i4.8802
Refbacks
- There are currently no refbacks.
