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The Impact of Intermittent Inhalation of Nitric Oxide on Hemodynamics in Patients with Obstructive Sleep Apnea (OSA) Complicated with Pulmonary Arterial Hypertension

Xiaofeng Wu, Wen Chen

Abstract


Patients with obstructive sleep apnea combined with pulmonary arterial hypertension often exhibit abnormalities in nocturnal hemodynamics. Focusing on the changes in pulmonary circulatory status before and after intermittent inhalation of nitric oxide, this study primarily
investigates the adjustment characteristics of pulmonary arterial pressure, pulmonary vascular resistance, and cardiac output status. The results
indicate that there is a consistent trend towards improvement in relevant hemodynamic indicators, with a significant reduction in the amplitude
of nocturnal fluctuations, which can provide a basis for the management of circulatory load in such patients.

Keywords


Obstructive Sleep Apnea; Pulmonary Arterial Hypertension; Inhaled Nitric Oxide; hemodynamics

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References


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DOI: http://dx.doi.org/10.70711/pmr.v3i5.8990

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