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Study on the Mechanism of Bacterial Resistance to Novel Antibiotics

Chunru Wei, Huixia Yu, Yanbo Bai

Abstract


Bacterial resistance to antibiotics is one of the major challenges in global public health. With the widespread use of antibiotics, the
rate at which bacteria develop resistance to antibiotics is increasing, causing multiple antibiotics to fail and threatening the existing healthcare
system. This article will explore in depth the mechanisms of bacterial resistance to novel antibiotics, analyze the currently known resistance
mechanisms, and discuss possible strategies to deal with bacterial resistance.

Keywords


Bacteria; Antibiotics; Bacterial resistance mechanism; Gene mutation

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References


[1] Davies J, Davies D.2010.Origins and Evolution of Antibiotic Resistance. Microbiol Mol Biol Rev74:.https://doi.org/10.1128/

mmbr.00016-10

[2] Luo C J, Xu J, Yang Z L.Clinical application and rational analysis of 174 cases of dattomycin [J]. Chinese Journal of Clinical Pharmacy,

2019, 32(10):752-757.

[3] Xu Yongcheng, Yu Xiaoxia, Wang Ying, et al. Effect of rifampicin pretreatment on the pharmacokinetics of linezolid [J]. Chinese Journal of Clinical Pharmacology, 2019, 40(10):1492-1496. (in Chinese)




DOI: http://dx.doi.org/10.70711/mhr.v2i4.5485

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