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The Effect of Transcranial Magnetic Stimulation Combined with Risperidone in the Treatment of Schizophrenia Patients and the Occurrence of Cognitive Function and Adverse Reactions

Shuai Gao, Xuejing Li, Xianqiang Zhang, Yuanhui Zhong, Desheng Li, Weiwei Yang

Abstract


Objective: To evaluate the efficacy of transcranial magnetic stimulation (TMS) combined with risperidone in the treatment of
schizophrenia, as well as the cognitive function and adverse reactions. Methods: The study period was from January 2024 to January 2025.
A total of 48 patients with schizophrenia who visited our hospital were collected as the research subjects. They were randomly divided into a
control group and an observation group, each consisting of 24 patients. The control group received risperidone alone, while the observation
group received TMS combined with risperidone. The treatment effects, cognitive functions, mental states, and adverse reactions of the two
groups were compared. Results: After treatment, the total effective rate of the observation group was higher than that of the control group
(P < 0.05). Before the implementation of different nursing plans, there was no significant difference in cognitive function and mental state
scores between the two groups. After the implementation, the cognitive function scores of the observation group were higher than those of the
control group, and the scores of various mental symptoms of the patients in the observation group were lower than those in the control group,
with statistically significant differences (P < 0.05). The incidence of adverse reactions after treatment in the observation group was relatively
lower, and the difference was statistically significant (P < 0.05). Conclusion: The combination of TMS and risperidone in the clinical treatment of schizophrenia has more prominent effects, significantly improves the mental symptoms and cognitive function of patients, and has
good safety, which is worthy of clinical adoption.

Keywords


Transcranial magnetic stimulation; Risperidone; Schizophrenia; Treatment effect; Cognitive function; Incidence of adverse reactions

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References


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DOI: http://dx.doi.org/10.70711/mhr.v2i7.7442

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