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Research Progress in mRNA Transcriptomics Sequencing in the Diagnosis and Treatment of OSAHS

Yisha Qin, Xuefeng Shi*

Abstract


Obstructive sleep apnoea-hypopnoea syndrome (OSAHS) is a complex sleep disorder caused by multiple mechanisms, including
intermittent hypoxia, sleep fragmentation, oxidative stress, and inflammatory responses. These mechanisms collectively lead to a series of
complex and diverse pathophysiological changes associated with the disease. In recent years, mRNA transcriptomics sequencing (RNA-Seq)
technology, as a high-throughput sequencing method, has increasingly become a powerful tool for revealing changes in gene expression and
regulatory mechanisms. In OSAHS research, by performing RNA-Seq on patient tissues or cells, it is possible to comprehensively analyse
gene expression profiles and uncover the molecular mechanisms closely associated with the disease. With the continuous advancement of transcriptomics sequencing technology and artificial intelligence analysis, mRNA transcriptomics analysis has demonstrated significant potential
in the diagnosis and treatment of OSAHS. It not only provides physicians with clues for early diagnosis and the development of personalised
treatment plans but also assists researchers in exploring new biomarkers and therapeutic targets, as well as assessing prognosis. By delving
deeper into mRNA transcriptomics data, researchers will be able to gain a more profound understanding of the pathophysiological processes
underlying OSAHS, driving breakthroughs in both scientific research and clinical practice in this field.

Keywords


mRNA transcriptomics sequencing; Obstructive sleep apnoea hypopnoea syndrome; Biomarkers; Gene expression analysis

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References


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DOI: http://dx.doi.org/10.70711/mhr.v2i7.7444

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